Symbol: Name: ID: |
TRPS1 trichorhinophalangeal syndrome I GFS:2152 |
Gene name: | TRPS1 |
Chromosome: | 8q23.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | LGCR |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1927616 | Rat Genome Database ID: | RGD:1311883 |
HGNC ID: | HGNC:12340 | RefSeq IDs: | NM_014112 |
Entrez Gene ID: | 7227 | Ensembl Gene ID: | ENSG00000104447 |
VEGA IDs: | OTTHUMG00000142829 | UniProt ID: | Q9UHF7 |
UCSC ID: | uc003yny.2 | OMIM ID: | 604386 |
Pubmed: | PMID8530105 PMID 10615131 PMID 10647898 | ||
CCDS IDs: | CCDSCCDS6318.2 |
Zinc finger transcription factor Trps1 is a protein that in humans is encoded by the TRPS1 gene. This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes.
Products for TRPS1 gene
Catalog | Product Name | Application | Company |
GFS:E02152 | trichorhinophalangeal syndrome I; ELISA kit | ELISA | n/a |
GFS:A02152 | trichorhinophalangeal syndrome I; Anti | ANTIBODIES | n/a |
GFS:P02152 | trichorhinophalangeal syndrome I; Protien | Protien | n/a |