| Symbol: Name: ID: |
TNPO3 transportin 3 GFS:6197 |
| Gene name: | TNPO3 |
| Chromosome: | 7q32.2 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | TRN-SR, MTR10A, TRN-SR2, IPO12 |
| Name Aliases: | importin 12 |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1196412 | Rat Genome Database ID: | RGD:1308938 |
| HGNC ID: | HGNC:17103 | RefSeq IDs: | NM_001191028 |
| Entrez Gene ID: | 23534 | Ensembl Gene ID: | ENSG00000064419 |
| VEGA IDs: | OTTHUMG00000158409 | UniProt ID: | Q9Y5L0 |
| UCSC ID: | uc003vol.1 | OMIM ID: | 610032 |
| Pubmed: | PMID10366588 PMID 10713112 | ||
| CCDS IDs: | CCDSCCDS5809.1 | ||
Transportin-3 is a protein that in humans is encoded by the TNPO3 gene.
The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010].
Function: Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins SFRS1 and SFRS2, by recognizing phosphorylated RS domains.
Products for TNPO3 gene
| Catalog | Product Name | Application | Company |
| GFS:E06197 | transportin 3; ELISA kit | ELISA | n/a |
| GFS:A06197 | transportin 3; Anti | ANTIBODIES | n/a |
| GFS:P06197 | transportin 3; Protien | Protien | n/a |
