| Symbol: Name: ID: |
TRAM2 translocation associated membrane protein 2 GFS:5942 |
| Gene name: | TRAM2 |
| Chromosome: | 6p21.1-p12 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | KIAA0057 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1924817 | Rat Genome Database ID: | RGD:1589151 |
| HGNC ID: | HGNC:16855 | RefSeq IDs: | NM_012288 |
| Entrez Gene ID: | 9697 | Ensembl Gene ID: | ENSG00000065308 |
| VEGA IDs: | OTTHUMG00000014850 | UniProt ID: | Q15035 |
| UCSC ID: | uc003paq.2 | OMIM ID: | 608485 |
| Pubmed: | PMID7584044 PMID 10594243 | ||
| CCDS IDs: | CCDSCCDS34477.1 | ||
Translocating chain-associated membrane protein 2 is a protein that in humans is encoded by the TRAM2 gene.
TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.[supplied by OMIM, Jul 2004].
Function: Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding.
Products for TRAM2 gene
| Catalog | Product Name | Application | Company |
| GFS:E05942 | translocation associated membrane protein 2; ELISA kit | ELISA | n/a |
| GFS:A05942 | translocation associated membrane protein 2; Anti | ANTIBODIES | n/a |
| GFS:P05942 | translocation associated membrane protein 2; Protien | Protien | n/a |
