| Symbol: Name: ID: |
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) GFS:1650 |
| Gene name: | TLE1 |
| Chromosome: | 9q21.32 |
| Previous Symbols: | |
| Previous Names: | transducin-like enhancer of split 1, homolog of Drosophila E(sp1) |
| Aliases: | ESG1, GRG1, ESG |
| Name Aliases: | enhancer of split groucho 1 |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:104636 | Rat Genome Database ID: | RGD:1309237 |
| HGNC ID: | HGNC:11837 | RefSeq IDs: | NM_005077 |
| Entrez Gene ID: | 7088 | Ensembl Gene ID: | ENSG00000196781 |
| VEGA IDs: | OTTHUMG00000021008 | UniProt ID: | Q04724 |
| UCSC ID: | uc004aly.2 | OMIM ID: | 600189 |
| Pubmed: | PMID8365415 PMID 8808280 | ||
| CCDS IDs: | CCDSCCDS6661.1 | ||
Transducin-like enhancer protein 1 is a protein that in humans is encoded by the TLE1 gene. Function: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Products for TLE1 gene
| Catalog | Product Name | Application | Company |
| GFS:E01650 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); ELISA kit | ELISA | n/a |
| GFS:A01650 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); Anti | ANTIBODIES | n/a |
| GFS:P01650 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); Protien | Protien | n/a |
