Symbol: Name: ID: |
TCN2 transcobalamin II GFS:1498 |
Gene name: | TCN2 |
Chromosome: | 22q12.2 |
Previous Symbols: | |
Previous Names: | transcobalamin II; macrocytic anemia |
Aliases: | D22S676, D22S750, TC2 |
Name Aliases: | macrocytic anemia |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98534 | Rat Genome Database ID: | RGD:620681 |
HGNC ID: | HGNC:11653 | RefSeq IDs: | NM_000355 |
Entrez Gene ID: | 6948 | Ensembl Gene ID: | |
VEGA IDs: | OTTHUMG00000151095 | UniProt ID: | P20062 |
UCSC ID: | uc003aip.1 | OMIM ID: | 613441 |
Pubmed: | PMID1708393 PMID 7742531 | ||
CCDS IDs: | CCDSCCDS13881.1 |
The TCN2 gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.
Function: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells.
Products for TCN2 gene
Catalog | Product Name | Application | Company |
GFS:E01498 | transcobalamin II; ELISA kit | ELISA | n/a |
GFS:A01498 | transcobalamin II; Anti | ANTIBODIES | n/a |
GFS:P01498 | transcobalamin II; Protien | Protien | n/a |