Symbol: Name: ID: |
TSTA3 tissue specific transplantation antigen P35B GFS:2192 |
Gene name: | TSTA3 |
Chromosome: | 8q24.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FX, P35B, SDR4E1 |
Name Aliases: | short chain dehydrogenase/reductase family 4E, member 1, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98857 | Rat Genome Database ID: | RGD:1307028 |
HGNC ID: | HGNC:12390 | RefSeq IDs: | NM_003313 |
Entrez Gene ID: | 7264 | Ensembl Gene ID: | ENSG00000104522 |
VEGA IDs: | UniProt ID: | Q13630 | |
UCSC ID: | uc003yzb.2 | OMIM ID: | 137020 |
Pubmed: | PMID7803801 PMID 1348494 PMID 19027726 | ||
CCDS IDs: | CCDSCCDS6408.1 |
GDP-L-fucose synthetase is an enzyme that in humans is encoded by the TSTA3 gene. Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq].
Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
Products for TSTA3 gene
Catalog | Product Name | Application | Company |
GFS:E02192 | tissue specific transplantation antigen P35B; ELISA kit | ELISA | n/a |
GFS:A02192 | tissue specific transplantation antigen P35B; Anti | ANTIBODIES | n/a |
GFS:P02192 | tissue specific transplantation antigen P35B; Protien | Protien | n/a |