Symbol: Name: ID: |
TRHR thyrotropin-releasing hormone receptor GFS:2115 |
Gene name: | TRHR |
Chromosome: | 8 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98824 | Rat Genome Database ID: | RGD:3904 |
HGNC ID: | HGNC:12299 | RefSeq IDs: | NM_003301 |
Entrez Gene ID: | 7201 | Ensembl Gene ID: | ENSG00000174417 |
VEGA IDs: | UniProt ID: | P34981 | |
UCSC ID: | uc003ymz.3 | OMIM ID: | 188545 |
Pubmed: | PMID8128317 | ||
CCDS IDs: | CCDSCCDS6311.1 |
The thyrotropin-releasing hormone receptor (TRHR) is a G protein-coupled receptor which binds the tripeptide thyrotropin releasing hormone. Thyrotropin-releasing hormone (TRH; MIM 275120), a small neuropeptide, is widely distributed throughout the central and peripheral nervous system as well as in extraneural tissues. The peptide is synthesized in the hypothalamus and transported by the portal vascular system to the anterior pituitary where it acts on thyrotropic and lactotropic cells to promote secretion of TSH and prolactin, respectively. Thyrotropin-releasing hormone receptor is a G protein-coupled receptor that activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon the binding of TRH. The TRHR gene is expressed in the thyrotrope cells of the anterior pituitary.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Products for TRHR gene
Catalog | Product Name | Application | Company |
GFS:E02115 | thyrotropin-releasing hormone receptor; ELISA kit | ELISA | n/a |
GFS:A02115 | thyrotropin-releasing hormone receptor; Anti | ANTIBODIES | n/a |
GFS:P02115 | thyrotropin-releasing hormone receptor; Protien | Protien | n/a |