Symbol: Name: ID: |
TSHR thyroid stimulating hormone receptor GFS:2177 |
Gene name: | TSHR |
Chromosome: | 14q24-q31 |
Previous Symbols: | |
Previous Names: | |
Aliases: | LGR3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98849 | Rat Genome Database ID: | RGD:3911 |
HGNC ID: | HGNC:12373 | RefSeq IDs: | NM_000369 |
Entrez Gene ID: | 7253 | Ensembl Gene ID: | ENSG00000165409 |
VEGA IDs: | OTTHUMG00000030029 | UniProt ID: | P16473 |
UCSC ID: | uc001xvd.1 | OMIM ID: | 603372 |
Pubmed: | PMID2558651 PMID 2610690 | ||
CCDS IDs: | CCDSCCDS9872.1 CCDS CCDS32131.1 |
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
Products for TSHR gene
Catalog | Product Name | Application | Company |
GFS:E02177 | thyroid stimulating hormone receptor; ELISA kit | ELISA | n/a |
GFS:A02177 | thyroid stimulating hormone receptor; Anti | ANTIBODIES | n/a |
GFS:P02177 | thyroid stimulating hormone receptor; Protien | Protien | n/a |