Symbol: Name: ID: |
TSPAN32 tetraspanin 32 GFS:3003 |
Gene name: | TSPAN32 |
Chromosome: | 11p15 |
Previous Symbols: | TSSC6, PHEMX |
Previous Names: | pan-hematopoietic expression |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1350360 | Rat Genome Database ID: | RGD:1590203 |
HGNC ID: | HGNC:13410 | RefSeq IDs: | NM_139022 |
Entrez Gene ID: | 10077 | Ensembl Gene ID: | ENSG00000064201 |
VEGA IDs: | OTTHUMG00000009762 | UniProt ID: | Q96QS1 |
UCSC ID: | uc001lvy.1 | OMIM ID: | 603853 |
Pubmed: | PMID10072438 PMID 10950922 | ||
CCDS IDs: | CCDSCCDS7733.1 |
Tetraspanin-32 is a protein that in humans is encoded by the TSPAN32 gene.
This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]. Sequence Note: A downstream start codon is selected for this RefSeq based on better conservation with homologs. The use of an alternative upstream start codon, which is present in primate species, would increase the protein length from 320 aa to 355 aa. The presence of a predicted signal anchor for the shorter, but not the longer, protein suggests that the downstream start codon may be preferentially used. The shorter protein is described in PMID 11718897.
Products for TSPAN32 gene
Catalog | Product Name | Application | Company |
GFS:E03003 | tetraspanin 32; ELISA kit | ELISA | n/a |
GFS:A03003 | tetraspanin 32; Anti | ANTIBODIES | n/a |
GFS:P03003 | tetraspanin 32; Protien | Protien | n/a |