Symbol: Name: ID: |
TXLNG taxilin gamma GFS:7421 |
Gene name: | TXLNG |
Chromosome: | Xp22.2 |
Previous Symbols: | CXorf15 |
Previous Names: | chromosome X open reading frame 15 |
Aliases: | FLJ11209, LSR5, FIAT, MGC126621, MGC126625 |
Name Aliases: | lipopolysaccharide specific response-5 protein, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3590652 | Rat Genome Database ID: | RGD:1564371 |
HGNC ID: | HGNC:18578 | RefSeq IDs: | NM_001168683 |
Entrez Gene ID: | 55787 | Ensembl Gene ID: | ENSG00000086712 |
VEGA IDs: | OTTHUMG00000021196 | UniProt ID: | Q9NUQ3 |
UCSC ID: | uc004cxq.1 | OMIM ID: | 300677 |
Pubmed: | PMID15911876 PMID 15184072 PMID 16831913 | ||
CCDS IDs: | CCDSCCDS14178.1 |
This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
Function: May be involved in intracellular vesicle traffic. Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA. May be involved in regulating bone mass density through an ATF4-dependent pathway. May be involved in cell cycle progression.
Products for TXLNG gene
Catalog | Product Name | Application | Company |
GFS:E07421 | taxilin gamma; ELISA kit | ELISA | n/a |
GFS:A07421 | taxilin gamma; Anti | ANTIBODIES | n/a |
GFS:P07421 | taxilin gamma; Protien | Protien | n/a |