| Symbol: Name: ID: |
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 GFS:6419 |
| Gene name: | TRNT1 |
| Chromosome: | 3p25.1 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | MtCCA, CGI-47, CCA1 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1917297 | Rat Genome Database ID: | RGD:1308857 |
| HGNC ID: | HGNC:17341 | RefSeq IDs: | NM_182916 |
| Entrez Gene ID: | 51095 | Ensembl Gene ID: | ENSG00000072756 |
| VEGA IDs: | OTTHUMG00000090259 | UniProt ID: | Q96Q11 |
| UCSC ID: | uc003bpp.3 | OMIM ID: | 612907 |
| Pubmed: | PMID10810093 PMID 11504732 | ||
| CCDS IDs: | CCDSCCDS2561.2 | ||
tRNA-nucleotidyltransferase 1, mitochondrial is an enzyme that in humans is encoded by the TRNT1 gene. This enzyme adds the nucleotide sequence CCA to the 3' end of tRNA, using ATP and CTP as substrates. The sequence creates the binding site for an amino acid.
The CCA-adding enzyme TRNT1 (EC 2.7.7.25) is an essential enzyme that catalyzes the addition of the CCA terminus to the 3-prime end of tRNA precursors. This reaction is a fundamental prerequisite for mature tRNAs to become aminoacylated and to participate in protein biosynthesis (Lizano et al., 2007 [PubMed 17204286]).[supplied by OMIM, Aug 2009].
Function: Adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and ATP as substrates.
Products for TRNT1 gene
| Catalog | Product Name | Application | Company |
| GFS:E06419 | tRNA nucleotidyl transferase, CCA-adding, 1; ELISA kit | ELISA | n/a |
| GFS:A06419 | tRNA nucleotidyl transferase, CCA-adding, 1; Anti | ANTIBODIES | n/a |
| GFS:P06419 | tRNA nucleotidyl transferase, CCA-adding, 1; Protien | Protien | n/a |
