Symbol: Name: ID: |
SSX4B synovial sarcoma, X breakpoint 4B GFS:5967 |
Gene name: | SSX4B |
Chromosome: | Xp11.23 |
Previous Symbols: | |
Previous Names: | |
Aliases: | OTTHUMT00000056510 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:16880 | RefSeq IDs: | NM_001034832 |
Entrez Gene ID: | 548313 | Ensembl Gene ID: | ENSG00000198946 |
VEGA IDs: | OTTHUMG00000021497 | UniProt ID: | O60224 |
UCSC ID: | uc004djh.1 | OMIM ID: | |
Pubmed: | |||
CCDS IDs: | CCDSCCDS35241.1 CCDS CCDS43935.1 |
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Function: Could act as a modulator of transcription.
Products for SSX4B gene
Catalog | Product Name | Application | Company |
GFS:E05967 | synovial sarcoma, X breakpoint 4B; ELISA kit | ELISA | n/a |
GFS:A05967 | synovial sarcoma, X breakpoint 4B; Anti | ANTIBODIES | n/a |
GFS:P05967 | synovial sarcoma, X breakpoint 4B; Protien | Protien | n/a |