Symbol: Name: ID: |
SNAP25 synaptosomal-associated protein, 25kDa GFS:1039 |
Gene name: | SNAP25 |
Chromosome: | 20p12-p11.2 |
Previous Symbols: | SNAP |
Previous Names: | synaptosomal-associated protein, 25kD |
Aliases: | SNAP-25, RIC-4, RIC4, SEC9, bA416N4.2, dJ1068F16.2 |
Name Aliases: | resistance to inhibitors of cholinesterase 4 homolog |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98331 | Rat Genome Database ID: | RGD:3728 |
HGNC ID: | HGNC:11132 | RefSeq IDs: | NM_003081 |
Entrez Gene ID: | 6616 | Ensembl Gene ID: | ENSG00000132639 |
VEGA IDs: | OTTHUMG00000031863 | UniProt ID: | P60880 |
UCSC ID: | uc002wnr.1 | OMIM ID: | 600322 |
Pubmed: | PMID8661740 PMID 10692432 | ||
CCDS IDs: | CCDSCCDS13109.1 CCDS CCDS13110.1 |
Synaptosomal-associated protein 25 (SNAP-25) is a protein that in humans is encoded by the SNAP25 gene. Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq].
t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
Products for SNAP25 gene
Catalog | Product Name | Application | Company |
GFS:E01039 | synaptosomal-associated protein, 25kDa; ELISA kit | ELISA | n/a |
GFS:A01039 | synaptosomal-associated protein, 25kDa; Anti | ANTIBODIES | n/a |
GFS:P01039 | synaptosomal-associated protein, 25kDa; Protien | Protien | n/a |