Symbol: Name: ID: |
SURF1 surfeit 1 GFS:1340 |
Gene name: | SURF1 |
Chromosome: | 9q33-q34 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | surfeit locus protein 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98443 | Rat Genome Database ID: | RGD:620527 |
HGNC ID: | HGNC:11474 | RefSeq IDs: | NM_003172 |
Entrez Gene ID: | 6834 | Ensembl Gene ID: | ENSG00000148290 |
VEGA IDs: | OTTHUMG00000020866 | UniProt ID: | Q15526 |
UCSC ID: | uc004cdh.1 | OMIM ID: | 185620 |
Pubmed: | PMID8499913 PMID 9843204 | ||
CCDS IDs: | CCDSCCDS6966.1 |
Surfeit locus protein 1 is a protein that in humans is encoded by the SURF1 gene. This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Probably involved in the biogenesis of the COX complex.
Products for SURF1 gene
Catalog | Product Name | Application | Company |
GFS:E01340 | surfeit 1; ELISA kit | ELISA | n/a |
GFS:A01340 | surfeit 1; Anti | ANTIBODIES | n/a |
GFS:P01340 | surfeit 1; Protien | Protien | n/a |