Symbol: Name: ID: |
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) GFS:1332 |
Gene name: | SUPT16H |
Chromosome: | 14q11.1 |
Previous Symbols: | |
Previous Names: | suppressor of Ty (S.cerevisiae) 16 homolog |
Aliases: | FACT, FACTP140, SPT16/CDC68, FLJ14010, FLJ10857, CDC68 |
Name Aliases: | facilitates chromatin remodeling 140 kDa subunit |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1890948 | Rat Genome Database ID: | RGD:1310032 |
HGNC ID: | HGNC:11465 | RefSeq IDs: | NM_007192 |
Entrez Gene ID: | 11198 | Ensembl Gene ID: | ENSG00000092201 |
VEGA IDs: | OTTHUMG00000029685 | UniProt ID: | Q9Y5B9 |
UCSC ID: | uc001wao.2 | OMIM ID: | 605012 |
Pubmed: | PMID9489704 PMID 11239457 | ||
CCDS IDs: | CCDSCCDS9569.1 |
FACT complex subunit SPT16 is a protein that in humans is encoded by the SUPT16H gene. Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for SUPT16H gene
Catalog | Product Name | Application | Company |
GFS:E01332 | suppressor of Ty 16 homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A01332 | suppressor of Ty 16 homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P01332 | suppressor of Ty 16 homolog (S. cerevisiae); Protien | Protien | n/a |