Symbol: Name: ID: |
SOD2 superoxide dismutase 2, mitochondrial GFS:1079 |
Gene name: | SOD2 |
Chromosome: | 6q25 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98352 | Rat Genome Database ID: | RGD:3732 |
HGNC ID: | HGNC:11180 | RefSeq IDs: | NM_000636 |
Entrez Gene ID: | 6648 | Ensembl Gene ID: | ENSG00000112096 |
VEGA IDs: | OTTHUMG00000015940 | UniProt ID: | P04179 |
UCSC ID: | uc003qsg.2 | OMIM ID: | 147460 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS5265.1 CCDS CCDS34564.1 |
Superoxide dismutase 2, mitochondrial, also known as SOD2, is an enzyme which in humans is encoded by the SOD2 gene. This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
Function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Products for SOD2 gene
Catalog | Product Name | Application | Company |
GFS:E01079 | superoxide dismutase 2, mitochondrial; ELISA kit | ELISA | n/a |
GFS:A01079 | superoxide dismutase 2, mitochondrial; Anti | ANTIBODIES | n/a |
GFS:P01079 | superoxide dismutase 2, mitochondrial; Protien | Protien | n/a |