Symbol: Name: ID: |
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 GFS:1330 |
Gene name: | SULT2B1 |
Chromosome: | 19q13.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | HSST2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1926342 | Rat Genome Database ID: | RGD:1308882 |
HGNC ID: | HGNC:11459 | RefSeq IDs: | NM_004605 |
Entrez Gene ID: | 6820 | Ensembl Gene ID: | ENSG00000088002 |
VEGA IDs: | UniProt ID: | O00204 | |
UCSC ID: | uc002pjl.2 | OMIM ID: | 604125 |
Pubmed: | PMID9799594 | ||
CCDS IDs: | CCDSCCDS12723.1 CCDS CCDS12724.1 |
Sulfotransferase family cytosolic 2B member 1 is an enzyme that in humans is encoded by the SULT2B1 gene. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq].
Catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol.
Products for SULT2B1 gene
Catalog | Product Name | Application | Company |
GFS:E01330 | sulfotransferase family, cytosolic, 2B, member 1; ELISA kit | ELISA | n/a |
GFS:A01330 | sulfotransferase family, cytosolic, 2B, member 1; Anti | ANTIBODIES | n/a |
GFS:P01330 | sulfotransferase family, cytosolic, 2B, member 1; Protien | Protien | n/a |