Symbol: Name: ID: |
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa GFS:601 |
Gene name: | SDHC |
Chromosome: | 1q21 |
Previous Symbols: | PGL3 |
Previous Names: | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1913302 | Rat Genome Database ID: | RGD:1359454 |
HGNC ID: | HGNC:10682 | RefSeq IDs: | NM_001035511 |
Entrez Gene ID: | 6391 | Ensembl Gene ID: | ENSG00000143252 |
VEGA IDs: | OTTHUMG00000034468 | UniProt ID: | Q99643 |
UCSC ID: | uc001gag.2 | OMIM ID: | 602413 |
Pubmed: | PMID9533030 PMID 12658451 | ||
CCDS IDs: | CCDSCCDS1230.1 CCDS CCDS41431.1 CCDS CCDS41432.1 CCDS CCDS44263.1 |
SDHC encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq].
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)
Products for SDHC gene
Catalog | Product Name | Application | Company |
GFS:E00601 | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa; ELISA kit | ELISA | n/a |
GFS:A00601 | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa; Anti | ANTIBODIES | n/a |
GFS:P00601 | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa; Protien | Protien | n/a |