Symbol: Name: ID: |
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit GFS:1319 |
Gene name: | SUCLA2 |
Chromosome: | 13q12.2-q13.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1306775 | Rat Genome Database ID: | RGD:1309397 |
HGNC ID: | HGNC:11448 | RefSeq IDs: | NM_003850 |
Entrez Gene ID: | 8803 | Ensembl Gene ID: | ENSG00000136143 |
VEGA IDs: | OTTHUMG00000016889 | UniProt ID: | Q9P2R7 |
UCSC ID: | uc001vbs.2 | OMIM ID: | 603921 |
Pubmed: | PMID9765291 | ||
CCDS IDs: | CCDSCCDS9406.1 |
Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial is an enzyme that in humans is encoded by the SUCLA2 gene. Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq].
Products for SUCLA2 gene
Catalog | Product Name | Application | Company |
GFS:E01319 | succinate-CoA ligase, ADP-forming, beta subunit; ELISA kit | ELISA | n/a |
GFS:A01319 | succinate-CoA ligase, ADP-forming, beta subunit; Anti | ANTIBODIES | n/a |
GFS:P01319 | succinate-CoA ligase, ADP-forming, beta subunit; Protien | Protien | n/a |