Symbol: Name: ID: |
STIP1 stress-induced-phosphoprotein 1 GFS:1270 |
Gene name: | STIP1 |
Chromosome: | 11q13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | HOP, STI1 |
Name Aliases: | Hsp70/Hsp90-organizing protein |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:109130 | Rat Genome Database ID: | RGD:621599 |
HGNC ID: | HGNC:11387 | RefSeq IDs: | NM_006819 |
Entrez Gene ID: | 10963 | Ensembl Gene ID: | ENSG00000168439 |
VEGA IDs: | UniProt ID: | P31948 | |
UCSC ID: | uc001nyk.1 | OMIM ID: | 605063 |
Pubmed: | PMID1569099 | ||
CCDS IDs: | CCDSCCDS8058.1 |
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB).
Products for STIP1 gene
Catalog | Product Name | Application | Company |
GFS:E01270 | stress-induced-phosphoprotein 1; ELISA kit | ELISA | n/a |
GFS:A01270 | stress-induced-phosphoprotein 1; Anti | ANTIBODIES | n/a |
GFS:P01270 | stress-induced-phosphoprotein 1; Protien | Protien | n/a |