Symbol: Name: ID: |
SFN stratifin GFS:691 |
Gene name: | SFN |
Chromosome: | 1p36.11 |
Previous Symbols: | |
Previous Names: | |
Aliases: | YWHAS |
Name Aliases: | 14-3-3 sigma |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1891831 | Rat Genome Database ID: | RGD:1304729 |
HGNC ID: | HGNC:10773 | RefSeq IDs: | NM_006142 |
Entrez Gene ID: | 2810 | Ensembl Gene ID: | ENSG00000175793 |
VEGA IDs: | OTTHUMG00000004093 | UniProt ID: | P31947 |
UCSC ID: | uc001bnc.1 | OMIM ID: | 601290 |
Pubmed: | PMID8515476 | ||
CCDS IDs: | CCDSCCDS288.1 |
14-3-3 protein sigma is a protein that in humans is encoded by the SFN gene. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity)
Function: p53-regulated inhibitor of G2/M progression
Products for SFN gene
Catalog | Product Name | Application | Company |
GFS:E00691 | stratifin; ELISA kit | ELISA | n/a |
GFS:A00691 | stratifin; Anti | ANTIBODIES | n/a |
GFS:P00691 | stratifin; Protien | Protien | n/a |