Symbol: Name: ID: |
SCP2 sterol carrier protein 2 GFS:529 |
Gene name: | SCP2 |
Chromosome: | 1p32 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98254 | Rat Genome Database ID: | RGD:3642 |
HGNC ID: | HGNC:10606 | RefSeq IDs: | NM_001007098 |
Entrez Gene ID: | 6342 | Ensembl Gene ID: | ENSG00000116171 |
VEGA IDs: | OTTHUMG00000008936 | UniProt ID: | P22307 |
UCSC ID: | uc001cur.1 | OMIM ID: | 184755 |
Pubmed: | PMID1703300 PMID 1718316 | ||
CCDS IDs: | CCDSCCDS572.1 CCDS CCDS30719.1 CCDS CCDS41338.1 CCDS CCDS44149.1 CCDS CCDS44150.1 |
SCP2 encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
Products for SCP2 gene
Catalog | Product Name | Application | Company |
GFS:E00529 | sterol carrier protein 2; ELISA kit | ELISA | n/a |
GFS:A00529 | sterol carrier protein 2; Anti | ANTIBODIES | n/a |
GFS:P00529 | sterol carrier protein 2; Protien | Protien | n/a |