Symbol: Name: ID: |
SARM1 sterile alpha and TIR motif containing 1 GFS:6168 |
Gene name: | SARM1 |
Chromosome: | 17q11 |
Previous Symbols: | |
Previous Names: | |
Aliases: | SARM, SAMD2, KIAA0524 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2136419 | Rat Genome Database ID: | RGD:1310078 |
HGNC ID: | HGNC:17074 | RefSeq IDs: | NM_015077 |
Entrez Gene ID: | 23098 | Ensembl Gene ID: | ENSG00000004139 |
VEGA IDs: | OTTHUMG00000132499 | UniProt ID: | Q6SZW1 |
UCSC ID: | uc010crl.1 | OMIM ID: | 607732 |
Pubmed: | PMID9628581 | ||
CCDS IDs: |
Function: Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.
Products for SARM1 gene
Catalog | Product Name | Application | Company |
GFS:E06168 | sterile alpha and TIR motif containing 1; ELISA kit | ELISA | n/a |
GFS:A06168 | sterile alpha and TIR motif containing 1; Anti | ANTIBODIES | n/a |
GFS:P06168 | sterile alpha and TIR motif containing 1; Protien | Protien | n/a |