Symbol: Name: ID: |
SART1 squamous cell carcinoma antigen recognized by T cells GFS:476 |
Gene name: | SART1 |
Chromosome: | 11q13.1 |
Previous Symbols: | |
Previous Names: | squamous cell carcinoma antigen recognised by T cells |
Aliases: | Ara1, Snu66, SNRNP110 |
Name Aliases: | small nuclear ribonucleoprotein 110kDa (U4/U6.U5) |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1309453 | Rat Genome Database ID: | RGD:61930 |
HGNC ID: | HGNC:10538 | RefSeq IDs: | NM_005146 |
Entrez Gene ID: | 9092 | Ensembl Gene ID: | ENSG00000175467 |
VEGA IDs: | UniProt ID: | O43290 | |
UCSC ID: | uc001ogl.2 | OMIM ID: | 605941 |
Pubmed: | PMID9449708 | ||
CCDS IDs: | CCDSCCDS31611.1 |
SART1 encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for SART1 gene
Catalog | Product Name | Application | Company |
GFS:E00476 | squamous cell carcinoma antigen recognized by T cells; ELISA kit | ELISA | n/a |
GFS:A00476 | squamous cell carcinoma antigen recognized by T cells; Anti | ANTIBODIES | n/a |
GFS:P00476 | squamous cell carcinoma antigen recognized by T cells; Protien | Protien | n/a |