Symbol: Name: ID: |
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 GFS:1055 |
Gene name: | SNRPB |
Chromosome: | 20p13 |
Previous Symbols: | SNRPB1 |
Previous Names: | |
Aliases: | COD, SmB/SmB, Sm-B/B, snRNP-B |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98342 | Rat Genome Database ID: | RGD:621301 |
HGNC ID: | HGNC:11153 | RefSeq IDs: | NM_003091 |
Entrez Gene ID: | 6628 | Ensembl Gene ID: | ENSG00000125835 |
VEGA IDs: | OTTHUMG00000031694 | UniProt ID: | P14678 |
UCSC ID: | uc002wfz.1 | OMIM ID: | 182282 |
Pubmed: | PMID1376292 | ||
CCDS IDs: | CCDSCCDS13026.1 CCDS CCDS13027.1 |
Small nuclear ribonucleoprotein-associated proteins B and B' is a protein that in humans is encoded by the SNRPB gene. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq].
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner (By similarity).
Products for SNRPB gene
Catalog | Product Name | Application | Company |
GFS:E01055 | small nuclear ribonucleoprotein polypeptides B and B1; ELISA kit | ELISA | n/a |
GFS:A01055 | small nuclear ribonucleoprotein polypeptides B and B1; Anti | ANTIBODIES | n/a |
GFS:P01055 | small nuclear ribonucleoprotein polypeptides B and B1; Protien | Protien | n/a |