Symbol: Name: ID: |
STEAP2 six transmembrane epithelial antigen of the prostate 2 GFS:6786 |
Gene name: | STEAP2 |
Chromosome: | 7q21.13 |
Previous Symbols: | PCANAP1 |
Previous Names: | prostate cancer associated protein 1 |
Aliases: | IPCA-1, STAMP1, STMP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1921301 | Rat Genome Database ID: | RGD:1307050 |
HGNC ID: | HGNC:17885 | RefSeq IDs: | NM_001040665 |
Entrez Gene ID: | 261729 | Ensembl Gene ID: | ENSG00000157214 |
VEGA IDs: | OTTHUMG00000023341 | UniProt ID: | Q8NFT2 |
UCSC ID: | uc003ujz.2 | OMIM ID: | 605094 |
Pubmed: | PMID10613842 PMID 12095985 | ||
CCDS IDs: | CCDSCCDS5615.1 CCDS CCDS43612.1 |
Metalloreductase STEAP2 is an enzyme that in humans is encoded by the STEAP2 gene.
This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Function: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).
Products for STEAP2 gene
Catalog | Product Name | Application | Company |
GFS:E06786 | six transmembrane epithelial antigen of the prostate 2; ELISA kit | ELISA | n/a |
GFS:A06786 | six transmembrane epithelial antigen of the prostate 2; Anti | ANTIBODIES | n/a |
GFS:P06786 | six transmembrane epithelial antigen of the prostate 2; Protien | Protien | n/a |