Symbol: Name: ID: |
SIRPG signal-regulatory protein gamma GFS:4907 |
Gene name: | SIRPG |
Chromosome: | 20p13 |
Previous Symbols: | SIRPB2 |
Previous Names: | signal-regulatory protein beta 2 |
Aliases: | bA77C3.1, SIRP-B2, SIRPgamma, CD172g |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:15757 | RefSeq IDs: | NM_001039508 |
Entrez Gene ID: | 55423 | Ensembl Gene ID: | ENSG00000089012 |
VEGA IDs: | OTTHUMG00000031680 | UniProt ID: | Q9P1W8 |
UCSC ID: | uc002wfm.1 | OMIM ID: | 605466 |
Pubmed: | PMID11185750 PMID 16339511 | ||
CCDS IDs: | CCDSCCDS13020.2 CCDS CCDS13021.2 CCDS CCDS33434.1 |
Signal-regulatory protein gamma is a protein that in humans is encoded by the SIRPG gene.
The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Function: Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
Products for SIRPG gene
Catalog | Product Name | Application | Company |
GFS:E04907 | signal-regulatory protein gamma; ELISA kit | ELISA | n/a |
GFS:A04907 | signal-regulatory protein gamma; Anti | ANTIBODIES | n/a |
GFS:P04907 | signal-regulatory protein gamma; Protien | Protien | n/a |