Symbol: Name: ID: |
SIRPB1 signal-regulatory protein beta 1 GFS:5060 |
Gene name: | SIRPB1 |
Chromosome: | 20p13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | SIRP-BETA-1, CD172b |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2444824 | Rat Genome Database ID: | |
HGNC ID: | HGNC:15928 | RefSeq IDs: | NM_001083910 |
Entrez Gene ID: | 10326 | Ensembl Gene ID: | ENSG00000101307 |
VEGA IDs: | OTTHUMG00000031676 | UniProt ID: | O00241 |
UCSC ID: | uc010gai.2 | OMIM ID: | 603889 |
Pubmed: | PMID9062191 PMID 16339511 | ||
CCDS IDs: | CCDSCCDS13019.1 CCDS CCDS42850.1 CCDS CCDS46571.1 |
Signal-regulatory protein beta-1 is a protein that in humans is encoded by the SIRPB1 gene. SIRPB1 has also recently been designated CD172B (cluster of differentiation 172B).
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].
Function: Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes (By similarity)
Products for SIRPB1 gene
Catalog | Product Name | Application | Company |
GFS:E05060 | signal-regulatory protein beta 1; ELISA kit | ELISA | n/a |
GFS:A05060 | signal-regulatory protein beta 1; Anti | ANTIBODIES | n/a |
GFS:P05060 | signal-regulatory protein beta 1; Protien | Protien | n/a |