Symbol: Name: ID: |
SIPA1 signal-induced proliferation-associated 1 GFS:793 |
Gene name: | SIPA1 |
Chromosome: | 11q13.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | SPA1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107576 | Rat Genome Database ID: | RGD:1303184 |
HGNC ID: | HGNC:10885 | RefSeq IDs: | NM_006747 |
Entrez Gene ID: | 6494 | Ensembl Gene ID: | ENSG00000213445 |
VEGA IDs: | UniProt ID: | Q96FS4 | |
UCSC ID: | uc001ofb.2 | OMIM ID: | 602180 |
Pubmed: | PMID9027487 | ||
CCDS IDs: | CCDSCCDS8108.1 |
Signal-induced proliferation-associated protein 1 is a protein that in humans is encoded by the SIPA1 gene. The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq].
GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting it to the putatively inactive GDP-bound state.
Products for SIPA1 gene
Catalog | Product Name | Application | Company |
GFS:E00793 | signal-induced proliferation-associated 1; ELISA kit | ELISA | n/a |
GFS:A00793 | signal-induced proliferation-associated 1; Anti | ANTIBODIES | n/a |
GFS:P00793 | signal-induced proliferation-associated 1; Protien | Protien | n/a |