Symbol: Name: ID: |
SELE selectin E GFS:636 |
Gene name: | SELE |
Chromosome: | 1q22-q25 |
Previous Symbols: | ELAM1, ELAM |
Previous Names: | endothelial adhesion molecule 1 |
Aliases: | ESEL, CD62E |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98278 | Rat Genome Database ID: | RGD:3654 |
HGNC ID: | HGNC:10718 | RefSeq IDs: | NM_000450 |
Entrez Gene ID: | 6401 | Ensembl Gene ID: | ENSG00000007908 |
VEGA IDs: | OTTHUMG00000034851 | UniProt ID: | P16581 |
UCSC ID: | uc001ggm.3 | OMIM ID: | 131210 |
Pubmed: | PMID1375831 | ||
CCDS IDs: | CCDSCCDS1283.1 |
The protein encoded by SELE is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis
Products for SELE gene
Catalog | Product Name | Application | Company |
GFS:E00636 | selectin E; ELISA kit | ELISA | n/a |
GFS:A00636 | selectin E; Anti | ANTIBODIES | n/a |
GFS:P00636 | selectin E; Protien | Protien | n/a |