Symbol: Name: ID: |
SCGB1D1 secretoglobin, family 1D, member 1 GFS:7253 |
Gene name: | SCGB1D1 |
Chromosome: | 11q13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | LPHA, LIPA, MGC71958 |
Name Aliases: | prostatein-like lipophilin A, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:18395 | RefSeq IDs: | NM_006552 |
Entrez Gene ID: | 10648 | Ensembl Gene ID: | ENSG00000168515 |
VEGA IDs: | UniProt ID: | O95968 | |
UCSC ID: | uc001nsz.1 | OMIM ID: | |
Pubmed: | PMID9720917 PMID 10066439 | ||
CCDS IDs: | CCDSCCDS8015.1 |
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. This gene product represents one component of a heterodimeric molecule present in human tears whose elution profile is consistent with prostatein, a tetrameric molecule composed of three peptide components in heterodimers. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 15, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008].
Function: May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.
Products for SCGB1D1 gene
Catalog | Product Name | Application | Company |
GFS:E07253 | secretoglobin, family 1D, member 1; ELISA kit | ELISA | n/a |
GFS:A07253 | secretoglobin, family 1D, member 1; Anti | ANTIBODIES | n/a |
GFS:P07253 | secretoglobin, family 1D, member 1; Protien | Protien | n/a |