Symbol: Name: ID: |
SCTR secretin receptor GFS:531 |
Gene name: | SCTR |
Chromosome: | 2q14.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2441720 | Rat Genome Database ID: | RGD:621342 |
HGNC ID: | HGNC:10608 | RefSeq IDs: | NM_002980 |
Entrez Gene ID: | 6344 | Ensembl Gene ID: | ENSG00000080293 |
VEGA IDs: | OTTHUMG00000131407 | UniProt ID: | P47872 |
UCSC ID: | uc002tma.2 | OMIM ID: | 182098 |
Pubmed: | PMID1646711 | ||
CCDS IDs: | CCDSCCDS2127.1 |
The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Secretin receptors are members of the glucagon receptor family that also includes glucagon, GLP-1, GLP-2, GHRH and GIP receptors. Secretin receptors are classically localized to the epithelial cells within the pancreatic and biliary ducts, where they stimulate the release of alkaline bicarbonate-rich fluid to neutralise acidic chyme from the stomach. This protects the duodenal mucosa and provides an optimal intraluminal environment for digestion to take place. Secretin receptors are also found in the CNS, where they are thought to play a role in the regulation of the hypothalamic-pituitary-axis (HPA) axis. The human secretin receptor gene is localized on chromosome 2p14.1.
Products for SCTR gene
Catalog | Product Name | Application | Company |
GFS:E00531 | secretin receptor; ELISA kit | ELISA | n/a |
GFS:A00531 | secretin receptor; Anti | ANTIBODIES | n/a |
GFS:P00531 | secretin receptor; Protien | Protien | n/a |