Symbol: Name: ID: |
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 GFS:382 |
Gene name: | RPS6KB1 |
Chromosome: | 17q23.1 |
Previous Symbols: | STK14A |
Previous Names: | ribosomal protein S6 kinase, 70kD, polypeptide 1 |
Aliases: | S6K1, p70(S6K)-alpha, PS6K |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1270849 | Rat Genome Database ID: | RGD:620683 |
HGNC ID: | HGNC:10436 | RefSeq IDs: | NM_003161 |
Entrez Gene ID: | 6198 | Ensembl Gene ID: | ENSG00000108443 |
VEGA IDs: | OTTHUMG00000150642 | UniProt ID: | P23443 |
UCSC ID: | uc002ixy.2 | OMIM ID: | 608938 |
Pubmed: | PMID1922062 | ||
CCDS IDs: | CCDSCCDS11621.1 |
RPS6KB1 encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for RPS6KB1 gene
Catalog | Product Name | Application | Company |
GFS:E00382 | ribosomal protein S6 kinase, 70kDa, polypeptide 1; ELISA kit | ELISA | n/a |
GFS:A00382 | ribosomal protein S6 kinase, 70kDa, polypeptide 1; Anti | ANTIBODIES | n/a |
GFS:P00382 | ribosomal protein S6 kinase, 70kDa, polypeptide 1; Protien | Protien | n/a |