Symbol: Name: ID: |
RAET1E retinoic acid early transcript 1E GFS:5877 |
Gene name: | RAET1E |
Chromosome: | 6q24.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | LETAL, bA350J20.7, ULBP4 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2675273 | Rat Genome Database ID: | |
HGNC ID: | HGNC:16793 | RefSeq IDs: | NM_139165 |
Entrez Gene ID: | 135250 | Ensembl Gene ID: | ENSG00000164520 |
VEGA IDs: | OTTHUMG00000015796 | UniProt ID: | Q8TD07 |
UCSC ID: | uc003qnl.1 | OMIM ID: | 609243 |
Pubmed: | PMID11827464 | ||
CCDS IDs: | CCDSCCDS5221.1 |
NKG2D ligand 4 is a protein that in humans is encoded by the RAET1E gene.
This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011].
Function: Ligand for the NKG2D receptor. Delivers activating signals to NK cells and promotes tumor immune surveillance by inducing the expansion of anti-tumor cytotoxic lymphocytes.
Products for RAET1E gene
Catalog | Product Name | Application | Company |
GFS:E05877 | retinoic acid early transcript 1E; ELISA kit | ELISA | n/a |
GFS:A05877 | retinoic acid early transcript 1E; Anti | ANTIBODIES | n/a |
GFS:P05877 | retinoic acid early transcript 1E; Protien | Protien | n/a |