Symbol: Name: ID: |
RAX retina and anterior neural fold homeobox GFS:7507 |
Gene name: | RAX |
Chromosome: | 18q21.31 |
Previous Symbols: | |
Previous Names: | |
Aliases: | RX |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:109632 | Rat Genome Database ID: | RGD:620371 |
HGNC ID: | HGNC:18662 | RefSeq IDs: | NM_013435 |
Entrez Gene ID: | 30062 | Ensembl Gene ID: | ENSG00000134438 |
VEGA IDs: | OTTHUMG00000132757 | UniProt ID: | Q9Y2V3 |
UCSC ID: | uc002lhx.2 | OMIM ID: | 601881 |
Pubmed: | PMID10625658 PMID 10766016 PMID 14662654 | ||
CCDS IDs: | CCDSCCDS11972.1 |
This gene encodes a homeobox-containing transcription factor that functions in eye development. The gene is expressed early in the eye primordia, and is required for retinal cell fate determination and also regulates stem cell proliferation. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia, and coloboma.[provided by RefSeq, Oct 2009].
Function: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
Products for RAX gene
Catalog | Product Name | Application | Company |
GFS:E07507 | retina and anterior neural fold homeobox; ELISA kit | ELISA | n/a |
GFS:A07507 | retina and anterior neural fold homeobox; Anti | ANTIBODIES | n/a |
GFS:P07507 | retina and anterior neural fold homeobox; Protien | Protien | n/a |