Symbol: Name: ID: |
RLN2 relaxin 2 GFS:28 |
Gene name: | RLN2 |
Chromosome: | 9pter-q12 |
Previous Symbols: | |
Previous Names: | relaxin 2 (H2) |
Aliases: | H2, RLXH2, bA12D24.1.1, bA12D24.1.2 |
Name Aliases: | relaxin H2, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:10027 | RefSeq IDs: | NM_005059 |
Entrez Gene ID: | 6019 | Ensembl Gene ID: | ENSG00000107014 |
VEGA IDs: | OTTHUMG00000019496 | UniProt ID: | P04090 |
UCSC ID: | uc003zja.1 | OMIM ID: | 179740 |
Pubmed: | PMID6548703 PMID 6548702 | ||
CCDS IDs: | CCDSCCDS6460.1 |
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq].
Products for RLN2 gene
Catalog | Product Name | Application | Company |
GFS:E00028 | relaxin 2; ELISA kit | ELISA | n/a |
GFS:A00028 | relaxin 2; Anti | ANTIBODIES | n/a |
GFS:P00028 | relaxin 2; Protien | Protien | n/a |