Symbol: Name: ID: |
RREB1 ras responsive element binding protein 1 GFS:395 |
Gene name: | RREB1 |
Chromosome: | 6p25 |
Previous Symbols: | |
Previous Names: | |
Aliases: | HNT |
Name Aliases: | hindsight homolog (drosophila) |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2443664 | Rat Genome Database ID: | RGD:1310904 |
HGNC ID: | HGNC:10449 | RefSeq IDs: | NM_001003698 |
Entrez Gene ID: | 6239 | Ensembl Gene ID: | ENSG00000124782 |
VEGA IDs: | OTTHUMG00000014201 | UniProt ID: | Q92766 |
UCSC ID: | uc003mxb.2 | OMIM ID: | 602209 |
Pubmed: | PMID9367691 PMID 18394891 | ||
CCDS IDs: | CCDSCCDS34335.1 CCDS CCDS34336.1 |
The protein encoded by RREB1 is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq].
Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1
Products for RREB1 gene
Catalog | Product Name | Application | Company |
GFS:E00395 | ras responsive element binding protein 1; ELISA kit | ELISA | n/a |
GFS:A00395 | ras responsive element binding protein 1; Anti | ANTIBODIES | n/a |
GFS:P00395 | ras responsive element binding protein 1; Protien | Protien | n/a |