Symbol: Name: ID: |
RHOU ras homolog gene family, member U GFS:6698 |
Gene name: | RHOU |
Chromosome: | 1q42.11-q42.3 |
Previous Symbols: | ARHU |
Previous Names: | |
Aliases: | WRCH-1, DJ646B12.2, FLJ10616, WRCH1, CDC42L1, hG28K, fJ646B12.2 |
Name Aliases: | Ryu GTPase, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1916831 | Rat Genome Database ID: | |
HGNC ID: | HGNC:17794 | RefSeq IDs: | NM_021205 |
Entrez Gene ID: | 58480 | Ensembl Gene ID: | ENSG00000116574 |
VEGA IDs: | OTTHUMG00000037919 | UniProt ID: | Q7L0Q8 |
UCSC ID: | uc001htf.2 | OMIM ID: | 606366 |
Pubmed: | PMID11459829 | ||
CCDS IDs: | CCDSCCDS1575.1 |
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011].
Function: Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound.
Products for RHOU gene
Catalog | Product Name | Application | Company |
GFS:E06698 | ras homolog gene family, member U; ELISA kit | ELISA | n/a |
GFS:A06698 | ras homolog gene family, member U; Anti | ANTIBODIES | n/a |
GFS:P06698 | ras homolog gene family, member U; Protien | Protien | n/a |