Symbol: Name: ID: |
PRKD2 protein kinase D2 GFS:6377 |
Gene name: | PRKD2 |
Chromosome: | 19q13.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | PKD2, HSPC187, DKFZP586E0820 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2141917 | Rat Genome Database ID: | RGD:1308054 |
HGNC ID: | HGNC:17293 | RefSeq IDs: | NM_001079880 |
Entrez Gene ID: | 25865 | Ensembl Gene ID: | ENSG00000105287 |
VEGA IDs: | UniProt ID: | Q9BZL6 | |
UCSC ID: | uc002pfj.2 | OMIM ID: | 607074 |
Pubmed: | PMID11042152 PMID 11062248 | ||
CCDS IDs: | CCDSCCDS12689.1 |
Serine/threonine-protein kinase D2 is an enzyme that in humans is encoded by the PRKD2 gene.
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Function: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity).
Products for PRKD2 gene
Catalog | Product Name | Application | Company |
GFS:E06377 | protein kinase D2; ELISA kit | ELISA | n/a |
GFS:A06377 | protein kinase D2; Anti | ANTIBODIES | n/a |
GFS:P06377 | protein kinase D2; Protien | Protien | n/a |