| Symbol: Name: ID: |
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 GFS:5974 |
| Gene name: | PSMD14 |
| Chromosome: | 2q14.3 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | POH1, pad1, Rpn11 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1913284 | Rat Genome Database ID: | RGD:1594532 |
| HGNC ID: | HGNC:16889 | RefSeq IDs: | NM_005805 |
| Entrez Gene ID: | 10213 | Ensembl Gene ID: | ENSG00000115233 |
| VEGA IDs: | OTTHUMG00000153882 | UniProt ID: | O00487 |
| UCSC ID: | uc002ubu.2 | OMIM ID: | 607173 |
| Pubmed: | PMID9374539 | ||
| CCDS IDs: | CCDSCCDS46437.1 | ||
26S proteasome non-ATPase regulatory subunit 14 is an enzyme that in humans is encoded by the PSMD14 gene.
PSMD14 is a component of the 26S proteasome, a multiprotein complex that degrades proteins targeted for destruction by the ubiquitin pathway (Spataro et al., 1997 [PubMed 9374539]).[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear.
Products for PSMD14 gene
| Catalog | Product Name | Application | Company |
| GFS:E05974 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14; ELISA kit | ELISA | n/a |
| GFS:A05974 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14; Anti | ANTIBODIES | n/a |
| GFS:P05974 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14; Protien | Protien | n/a |
