Symbol: Name: ID: |
PDCD11 programmed cell death 11 GFS:3002 |
Gene name: | PDCD11 |
Chromosome: | 10q24.32 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0185, ALG-4, RRP5 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1341788 | Rat Genome Database ID: | RGD:1304933 |
HGNC ID: | HGNC:13408 | RefSeq IDs: | NM_014976 |
Entrez Gene ID: | 22984 | Ensembl Gene ID: | ENSG00000148843 |
VEGA IDs: | OTTHUMG00000018988 | UniProt ID: | Q14690 |
UCSC ID: | uc001kwy.1 | OMIM ID: | 612333 |
Pubmed: | PMID10229231 | ||
CCDS IDs: | CCDSCCDS31276.1 |
PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplied by OMIM].
Function: Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA .
Function: Involved in the biogenesis of rRNA (By similarity).
Products for PDCD11 gene
Catalog | Product Name | Application | Company |
GFS:E03002 | programmed cell death 11; ELISA kit | ELISA | n/a |
GFS:A03002 | programmed cell death 11; Anti | ANTIBODIES | n/a |
GFS:P03002 | programmed cell death 11; Protien | Protien | n/a |