Symbol: Name: ID: |
PTBP2 polypyrimidine tract binding protein 2 GFS:6611 |
Gene name: | PTBP2 |
Chromosome: | 1p21.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | brPTB, nPTB, PTB, PTBLP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1860489 | Rat Genome Database ID: | RGD:1359267 |
HGNC ID: | HGNC:17662 | RefSeq IDs: | NM_021190 |
Entrez Gene ID: | 58155 | Ensembl Gene ID: | ENSG00000117569 |
VEGA IDs: | OTTHUMG00000010685 | UniProt ID: | Q9UKA9 |
UCSC ID: | uc001drq.2 | OMIM ID: | 608449 |
Pubmed: | PMID11003644 | ||
CCDS IDs: | CCDSCCDS754.1 |
The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. Beside its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.
Products for PTBP2 gene
Catalog | Product Name | Application | Company |
GFS:E06611 | polypyrimidine tract binding protein 2; ELISA kit | ELISA | n/a |
GFS:A06611 | polypyrimidine tract binding protein 2; Anti | ANTIBODIES | n/a |
GFS:P06611 | polypyrimidine tract binding protein 2; Protien | Protien | n/a |