| Symbol: Name: ID: |
POLE3 polymerase (DNA directed), epsilon 3 (p17 subunit) GFS:3099 |
| Gene name: | POLE3 |
| Chromosome: | 9q33 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | CHRAC17, Ybl1, p17, CHARAC17 |
| Name Aliases: | histone fold protein CHRAC17, |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1933378 | Rat Genome Database ID: | RGD:1359475 |
| HGNC ID: | HGNC:13546 | RefSeq IDs: | NM_017443 |
| Entrez Gene ID: | 54107 | Ensembl Gene ID: | ENSG00000148229 |
| VEGA IDs: | OTTHUMG00000020523 | UniProt ID: | Q9NRF9 |
| UCSC ID: | uc004bhn.2 | OMIM ID: | 607267 |
| Pubmed: | PMID10801849 PMID 10880450 | ||
| CCDS IDs: | CCDSCCDS6795.1 | ||
DNA polymerase epsilon subunit 3 is an enzyme that in humans is encoded by the POLE3 gene.
POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004].
Function: Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.
Products for POLE3 gene
| Catalog | Product Name | Application | Company |
| GFS:E03099 | polymerase (DNA directed), epsilon 3 (p17 subunit); ELISA kit | ELISA | n/a |
| GFS:A03099 | polymerase (DNA directed), epsilon 3 (p17 subunit); Anti | ANTIBODIES | n/a |
| GFS:P03099 | polymerase (DNA directed), epsilon 3 (p17 subunit); Protien | Protien | n/a |
