Symbol: Name: ID: |
PHC3 polyhomeotic homolog 3 (Drosophila) GFS:4850 |
Gene name: | PHC3 |
Chromosome: | 3q26.32 |
Previous Symbols: | |
Previous Names: | polyhomeotic like 3 (Drosophila) |
Aliases: | EDR3, FLJ12967, FLJ12729, HPH3 |
Name Aliases: | early development regulator 3, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2181434 | Rat Genome Database ID: | RGD:1307998 |
HGNC ID: | HGNC:15682 | RefSeq IDs: | NM_024947 |
Entrez Gene ID: | 80012 | Ensembl Gene ID: | ENSG00000173889 |
VEGA IDs: | OTTHUMG00000158777 | UniProt ID: | Q8NDX5 |
UCSC ID: | uc003fgl.2 | OMIM ID: | |
Pubmed: | PMID12167701 PMID 12384788 | ||
CCDS IDs: | CCDSCCDS46952.1 |
Polyhomeotic-like protein 3 is a protein that in humans is encoded by the PHC3 gene.
Function: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Products for PHC3 gene
Catalog | Product Name | Application | Company |
GFS:E04850 | polyhomeotic homolog 3 (Drosophila); ELISA kit | ELISA | n/a |
GFS:A04850 | polyhomeotic homolog 3 (Drosophila); Anti | ANTIBODIES | n/a |
GFS:P04850 | polyhomeotic homolog 3 (Drosophila); Protien | Protien | n/a |