| Symbol: Name: ID: |
PAIP2 poly(A) binding protein interacting protein 2 GFS:6866 |
| Gene name: | PAIP2 |
| Chromosome: | 5q32 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | PAIP2A |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1915119 | Rat Genome Database ID: | RGD:1359176 |
| HGNC ID: | HGNC:17970 | RefSeq IDs: | NM_001033112 |
| Entrez Gene ID: | 51247 | Ensembl Gene ID: | ENSG00000120727 |
| VEGA IDs: | OTTHUMG00000129227 | UniProt ID: | Q9BPZ3 |
| UCSC ID: | uc003led.2 | OMIM ID: | 605604 |
| Pubmed: | PMID11172725 PMID 16804161 | ||
| CCDS IDs: | CCDSCCDS4211.1 | ||
Polyadenylate-binding protein-interacting protein 2 is a protein that in humans is encoded by the PAIP2 gene.
Function: Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Products for PAIP2 gene
| Catalog | Product Name | Application | Company |
| GFS:E06866 | poly(A) binding protein interacting protein 2; ELISA kit | ELISA | n/a |
| GFS:A06866 | poly(A) binding protein interacting protein 2; Anti | ANTIBODIES | n/a |
| GFS:P06866 | poly(A) binding protein interacting protein 2; Protien | Protien | n/a |
