Symbol: Name: ID: |
PLSCR2 phospholipid scramblase 2 GFS:5602 |
Gene name: | PLSCR2 |
Chromosome: | 3q24 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:16494 | RefSeq IDs: | NM_001199978 |
Entrez Gene ID: | 57047 | Ensembl Gene ID: | ENSG00000163746 |
VEGA IDs: | OTTHUMG00000159429 | UniProt ID: | Q9NRY7 |
UCSC ID: | uc003evv.1 | OMIM ID: | 607610 |
Pubmed: | PMID10930526 | ||
CCDS IDs: |
This gene encodes a member of the phospholipid scramblase family. Phospholipid scramblases are membrane proteins that mediate calcium-dependent, non-specific movement of plasma membrane phospholipids and phosphatidylserine exposure. The encoded protein contains a low affinity calcium binding motif and may play a role in blood coagulation and apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq)
Function: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
Products for PLSCR2 gene
Catalog | Product Name | Application | Company |
GFS:E05602 | phospholipid scramblase 2; ELISA kit | ELISA | n/a |
GFS:A05602 | phospholipid scramblase 2; Anti | ANTIBODIES | n/a |
GFS:P05602 | phospholipid scramblase 2; Protien | Protien | n/a |