Symbol: Name: ID: |
PIGS phosphatidylinositol glycan anchor biosynthesis, class S GFS:4221 |
Gene name: | PIGS |
Chromosome: | 17p13.2 |
Previous Symbols: | |
Previous Names: | phosphatidylinositol glycan, class S |
Aliases: | |
Name Aliases: | GPI transamidase subunit |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2687325 | Rat Genome Database ID: | RGD:1359436 |
HGNC ID: | HGNC:14937 | RefSeq IDs: | NM_033198 |
Entrez Gene ID: | 94005 | Ensembl Gene ID: | ENSG00000087111 |
VEGA IDs: | OTTHUMG00000132604 | UniProt ID: | Q96S52 |
UCSC ID: | uc002hbo.2 | OMIM ID: | 610271 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS11235.1 |
GPI transamidase component PIG-S is an enzyme that in humans is encoded by the PIGS gene.
This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008].
Function: Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates.
Products for PIGS gene
Catalog | Product Name | Application | Company |
GFS:E04221 | phosphatidylinositol glycan anchor biosynthesis, class S; ELISA kit | ELISA | n/a |
GFS:A04221 | phosphatidylinositol glycan anchor biosynthesis, class S; Anti | ANTIBODIES | n/a |
GFS:P04221 | phosphatidylinositol glycan anchor biosynthesis, class S; Protien | Protien | n/a |