Symbol: Name: ID: |
PLIN3 perilipin 3 GFS:5979 |
Gene name: | PLIN3 |
Chromosome: | 19p13.3 |
Previous Symbols: | M6PRBP1 |
Previous Names: | mannose-6-phosphate receptor binding protein 1 |
Aliases: | TIP47, PP17 |
Name Aliases: | cargo selection protein (mannose 6 phosphate receptor binding protein), |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1914155 | Rat Genome Database ID: | RGD:1595854 |
HGNC ID: | HGNC:16893 | RefSeq IDs: | NM_001164189 |
Entrez Gene ID: | 10226 | Ensembl Gene ID: | ENSG00000105355 |
VEGA IDs: | UniProt ID: | O60664 | |
UCSC ID: | uc002mbj.2 | OMIM ID: | 602702 |
Pubmed: | PMID9590177 PMID 6856484 PMID 19638644 | ||
CCDS IDs: | CCDSCCDS12137.1 |
Mannose-6-phosphate receptor binding protein 1 (M6PRBP1) is a protein which in humans is encoded by the M6PRBP1 gene. Its gene product, as well as the gene itself, is commonly known as TIP47.
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2009].
Function: Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
Products for PLIN3 gene
Catalog | Product Name | Application | Company |
GFS:E05979 | perilipin 3; ELISA kit | ELISA | n/a |
GFS:A05979 | perilipin 3; Anti | ANTIBODIES | n/a |
GFS:P05979 | perilipin 3; Protien | Protien | n/a |