Symbol: Name: ID: |
PPIH peptidylprolyl isomerase H (cyclophilin H) GFS:3941 |
Gene name: | PPIH |
Chromosome: | 1p34.1 |
Previous Symbols: | |
Previous Names: | peptidyl prolyl isomerase H (cyclophilin H) |
Aliases: | USA-CYP, CYP-20, SnuCyp-20, CYPH, MGC5016 |
Name Aliases: | USA-CyP SnuCyp-20, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:106499 | Rat Genome Database ID: | RGD:1564921 |
HGNC ID: | HGNC:14651 | RefSeq IDs: | NM_006347 |
Entrez Gene ID: | 10465 | Ensembl Gene ID: | ENSG00000171960 |
VEGA IDs: | OTTHUMG00000007520 | UniProt ID: | O43447 |
UCSC ID: | uc001chq.2 | OMIM ID: | 606095 |
Pubmed: | PMID9404889 PMID 9570313 | ||
CCDS IDs: | CCDSCCDS469.1 |
Peptidyl-prolyl cis-trans isomerase H is an enzyme that in humans is encoded by the PPIH gene.
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome. [provided by RefSeq, Jul 2008].
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex. May act as a chaperone.
Products for PPIH gene
Catalog | Product Name | Application | Company |
GFS:E03941 | peptidylprolyl isomerase H (cyclophilin H); ELISA kit | ELISA | n/a |
GFS:A03941 | peptidylprolyl isomerase H (cyclophilin H); Anti | ANTIBODIES | n/a |
GFS:P03941 | peptidylprolyl isomerase H (cyclophilin H); Protien | Protien | n/a |