Symbol: Name: ID: |
PARVB parvin, beta GFS:3943 |
Gene name: | PARVB |
Chromosome: | 22q13.2-q13.33 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CGI-56 |
Name Aliases: | affixin |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2153063 | Rat Genome Database ID: | RGD:1311485 |
HGNC ID: | HGNC:14653 | RefSeq IDs: | NM_001003828 |
Entrez Gene ID: | 29780 | Ensembl Gene ID: | ENSG00000188677 |
VEGA IDs: | OTTHUMG00000150665 | UniProt ID: | Q9HBI1 |
UCSC ID: | uc003ben.2 | OMIM ID: | 608121 |
Pubmed: | PMID10810093 PMID 11171322 | ||
CCDS IDs: | CCDSCCDS14056.1 CCDS CCDS46724.1 |
Beta-parvin is a protein that in humans is encoded by the PARVB gene.
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011].
Function: Probably plays a role in the regulation of cell adhesion and cytoskeleton organization.
Products for PARVB gene
Catalog | Product Name | Application | Company |
GFS:E03943 | parvin, beta; ELISA kit | ELISA | n/a |
GFS:A03943 | parvin, beta; Anti | ANTIBODIES | n/a |
GFS:P03943 | parvin, beta; Protien | Protien | n/a |